Gene Technology

Study Guide

Read pages 153-167

Define the following:

1.    Recombinant DNA- Molecule formed when fragments of DNA from two or more different organisms are spliced together.

 

2.    Genetic engineering- The process of moving genes from the chromosomes of one organism to those of another.

 

3.    Restriction enzyme- Enzyme that recognizes and blinds to specific short sequences of DNA

 

4.    Plasmid- Small, circular DNA molecules found in cytoplasm of bacteria

 

5.    Vector- Agent used to transfer genes in genetic engineering.

 

6.    Nitrogen fixation- Conversion of atmospheric nitrogen to ammonia by bacteria 

 

7.    Vaccine- A preparation of killed or weakened pathogens introducing into the body to produce immunity.

 

8.    Antibody- Defensive protein produced by white blood cells in response to a foreign substance, released by B cells.

 

9.    DNA fingerprints- A pattern of dark bands that reflects the composition of an organism’s DNA

 

10.                       Human genome- Entire collection of genes within human cells.

 

11.                       What kinds of vaccinations have you received?

 

12.                       How is a vaccine prepared?

 

 

 

 

 

 

 

13.                       Which of the following statements do you agree or disagree with?

 

 

Using genetic engineering scientist are making certain plants more disease resistant.

 

Using genetic engineering scientist are making growing numbers of pharmaceutical

products.

 

Every organisms has a unique set of DNA

 

 

14.                       Which two organisms were used to make the first Recombinant DNA?- A frog and bacteria

 

15.                       What is Recombinant DNA?- A molecule formed when fragments of DNA from two or more different organisms are sliced together in a laboratory.

 

16.                       What is genetic engineering?-The process of moving genes from the chromosomes of one organism to those of another.

 

17.                       What does it mean to have single-stranded tails on DNA?- “Sticky Ends” can pair back up or seal the break.

 

18.                       What cuts DNA into pieces  with sticky ends?- Enzymes restriction

 

19.                       EcoRI cuts DNA when it encounters what base sequence?- CTTAAG

 

20.                       What are plasmids?-Small, circular DNA molecules found in the cytoplasm of bacteria which allowed enzymes to cut and shake them have sticky ends.

 

21.                       How dies genetic code support the theory that all organisms have the same design?- The genetic code is universal for all organisms, from bacteria to humans.

 

22.                       How many restriced enzymes besides EcoRI have been isolated, making it possible to cleave a DNA molecule at more than 90 sites?-200

 

23.                       What are the 4 stages to genetic engineering?-1) Cleaving DNA, 2) Producing recombinant DNA, 3) Cloning target cells, 4)Screening target cells.

 

 

24.                       How are restriction enzymes used in gene transfer experiments?-Restriction enzymes recognize and cleave specific sites along the DNA molecule leaving fragments with sticky ends.

 

25.                       How do scientist ensure that microorganisms used in genetic engineering experiments will not cause damage?- Scientists select target  cells that cannot survive outside the laboratory.  Scientist follow strict rules stating this.

 

26.                       What are some implications of genetic engineering?-Preventing and curing illnesses, milk production in cows, disease resistant plant crops, and drugs manufactured of human proteins, and large amounts of insulin.

 

27.                       What are Ti plasmids?- A circular molecule of DNA that possesses the gene responsible for the plant tumors, can be used to transfer genes.

 

28.                       How could genetic engineer make meat healther?-Leaner

 

29.                       What are the goals of the Human Genome Project? To locate, catalog, and sequence every human gene.

 

30.                       Write an essay on DNA fingerprinting. Use resources Summarize 5 ways DNA finger-printing is being used today to answer questions.